Nanomaterial Information

Symbol SiO2
Name Silica, fumed
Source Sigma #S5505, St. Louis, MO

Dispersant  -
Size Diameter: 200-300 nm
Aggregate Size[1] 221.8 ± 17.7 nm
-1.19 µm/(V/cm)-s 
Refractive Index 1.46

Toxicity test method

Suspension preparation method
10 mg / 50 mg SiO2 was add to 10 mL/50 mL ultrapure water generated by a Barnstead EPure system (Thermo Fisher Scientific, Waltham, MA) in a 10 -mL / 50 -mL centrifuge tube, and sonicated in a sonicating cup horn ( sonics & Material, Newtown, CT) at 100 W for 30 min. The samples were stored at room temperature in 10 -mL / 50 -mL centrifuge tubes wrapped in aluminum foil before use within 6 months.

Particle size measurement method

ENM electrophoretic mobility measurement.


  1. Number mean hydrodynamic diameter nm. Measured by dynamic light scattering (Zetasizer Nano, Malvern, Worcestershire, UK)
  2. Measured at ~pH 5.

Go to Toxicity page